MetforminD6hydrochloride是Metforminhydrochloride的一种氘代化合物。Metforminhydrochloride抑制肝脏中的线粒体呼吸链，导致AMPK活化，增强胰岛素敏感性，可用于2型糖尿病的研究。Metforminhydrochloride可以透过血脑屏障，诱导自噬(autophagy)。
货号:ajcx31028
CAS:1185166-01-1
分子式:C4H6D6ClN5
分子量：171.66
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Metformin D6 hydrochloride is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy[1].

[1]. Soraya H, et al. Acute treatment with metformin improves cardiac function following NSC 37745 induced myocardial infarction in rats. Pharmacol Rep. 2012;64(6):1476-84.