MMAE-SMCC 是由有效的有丝分裂和微管蛋白抑制剂 MMAE 和接头 SMCC 组成的抗体偶联药物，可制成抗体药物偶联物。
货号:ajcx34154
CAS:2021179-11-1
分子式:C58H89N7O14S
分子量：1140.43
溶解度:DMSO : 220 mg/mL (192.91 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate[1].

[1]. Tang F, et al. One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates. Org Biomol Chem. 2016 Oct 12;14(40):9501-9518.