Dasatinib metabolite M6 (Dasatinib carboxylic acid) 是 Dasatinib 的氧化代谢物。Dasatinib 是一种具有口服活性的，ATP 竞争性的，双重 Src/Bcr-Abl 抑制剂，具有有效的抗肿瘤活性。
货号:ajcx34674
CAS:910297-53-9
分子式:C22H24ClN7O3S
分子量：501.99
溶解度:DMSO : 100 mg/mL (199.21 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib . Dasatinib is a potent and orally active dual Bcr-Abl and Src family tyrosine kinase inhibitor[1].

[1]. Lisa J Christopher, et al. Biotransformation of [14C]dasatinib: in vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys. Drug Metab Dispos. 2008 Jul;36(7):1341-56.