IRAK4-IN-6 是一种口服高效、选择性 IRAK 抑制剂，IC50 为 4 nM，靶向 MyD88 L265P 突变型弥漫性大 B 细胞淋巴瘤。
货号:ajcx32756
CAS:2454244-02-9
分子式:C25H32N10O2
分子量：504.59
溶解度:DMSO : 125 mg/mL (247.73 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma[1].

参考文献:
[1]. Degorce SL, et al. Discovery of a Series of 5-Azaquinazolines as Orally Efficacious IRAK4 Inhibitors TargetingMyD88L265P Mutant Diffuse Large B Cell Lymphoma. J Med Chem. 2019 Nov 1.