Kamebakaurin 是从 Isodon japonicus 中提取的一种天然产物。Kamebakaurin 是 NF-κB 的抑制剂，可抑制 p50 的 DNA 结合活性。
货号:ajcx15968
CAS:73981-34-7
分子式:C20H30O5
分子量：350.45
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Kamebakaurin is a natural compound isolated from Isodon japonicus. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1].

[1]. Lee JH, et al. Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. J Biol Chem. 2002 May 24;277(21):18411-20.