Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) 是一种合成的 E3 连接酶配体 -linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 2 个单元的 PEG linker，应用于 PROTAC 技术。
货号:ajcx15506
CAS:2098487-52-4
分子式:C20H20N2O7
分子量：400.38
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.