1-Ethynylpyrene是细胞色素P4501A1,1A2和2B1的抑制剂，IC50分别为0.18，0.32和0.04μM。
货号:ajcx29892
CAS:34993-56-1
分子式:C18H10
分子量：226.27
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively[1].

1-Ethynylpyrene exhibits activity against P450 1A2, and 2B1 with Kis of 0.32 and 0.04 μM, respectively[1].

[1]. Naijue Zhu, et al. Ethynyl and Propynylpyrene Inhibitors of Cytochrome P450. J Chem Crystallogr. 2010 Apr 1;40(4):343-352.