| CAS NO: | 116477-57-7 |
| 规格: | 98% |
| 分子量: | 318.5 |
| 包装 | 价格(元) |
| 25ug | 电议 |
| 50ug | 电议 |
| 100ug | 电议 |
Background:
20-HEPE is a metabolite of eicosapentaenoic acid that is formed via ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. It activates peroxisome proliferator-activated receptor α (PPARα) in COS-7 cells expressing a luciferase reporter when used at a concentration of 10 μM. 20-HEPE also activates murine transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks antinociceptive activity in rats.
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