Prostaglandin D2 (PGD2) evokes its effects through two receptors, DP1 and CRTH2/DP2.
CAS：916048-02-7
分子式：C17H19ClN2O4
分子量：350.8
纯度：98%
存储：Store at -20°C

Background:

Prostaglandin D2 (PGD2) evokes its effects through two receptors, DP1 and CRTH2/DP2. The activation of DP2 leads to eosinophil chemotaxis, activation, and degranulation as well as recruitment of basophils and lymphocytes and, as a result, is important in allergic inflammatory disease. CAY10648 is an intermediate used in the synthesis of potent DP2 receptor antagonists based on a novel spiro-indolinone compound.