MAK-683 (MAK683; extracted from patent US20160176882 A1, compound example 2) is a novel and potent embryonic ectoderm development protein (EED) inhibitor and allosteric inhibitor of polycomb repressive complex 2 (PRC2) with potential anticancer activity. It inhibits EED and PRC2 with IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay.

纯度：≥98%

CAS：1951408-58-4