HPV16-E711-20 epitope 是 HLA-A*0201 限制性人细胞毒性T淋巴细胞 (CTL) 表位的 HPV16 E7 蛋白，在体外显示了与 HLA-A2 的高亲和力结合。HPV16 CTL 表位可能是开发有效肽基抗肿瘤疫苗的良好候选。
CAS：160040-04-0
分子式：C53H83N11O19S
分子量：1210.35
纯度：98%
存储：Store at -20°C

Background:

HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. HPV16 CTL epitopes may be good candidates for the development of an effective peptide-based antitumor vaccine[1].

[1]. Ding Z, et al. Cytolytic activity of the human papillomavirus type 16 E711-20 epitope-specific cytotoxic T lymphocyte is enhanced by heat shock protein 110 in HLA-A*0201 transgenic mice. Clin Vaccine Immunol. 2013 Jul;20(7):1027-33.