| CAS NO: | 133538-58-6 |
| 规格: | 98% |
| 分子量: | 531.4 |
| 包装 | 价格(元) |
| 100ug | 电议 |
| 500ug | 电议 |
| 1mg | 电议 |
Background:
I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and 490 pM at pH 6.5.
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