DMT1 blocker 2, Compound 12f，是二价金属转运蛋白1 (DMT1) 的直接抑制剂，IC50为 0.83 μM，可以阻断体内肠细胞的铁摄取。
CAS：1062648-63-8
分子式：C16H13N3O
分子量：263.29
纯度：98%
存储：Store at -20°C

Background:

DMT1 blocker 2, Compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 of 0.83 μM, is expected to block iron uptake by enterocytes in vivo[1].

IC50: 0.83 μM (DMT1 blocker 2)[1]

[1]. Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.