GDC-0927Racemate(SRN-927Racemate)是雌激素受体(estrogenreceptor)的降解剂，能够有效抑制ER-α的活性，IC50值为0.2nM，可用于雌激素受体有关的疾病。
CAS：1443983-36-5
分子式：C28H28FNO4
分子量：461.52
纯度：98%
存储：Store at -20°C

Background:

GDC-0927 Racemate (SRN-927 Racemate) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases.

GDC-0927 Racemate (Example 1) is a degrader of estrogen receptor, potently inhibits ER-α activity, with an IC50 of 0.2 nM, and is used in the research of ER-related diseases. GDC-0927 Racemate reduces the viability of MCF7 cells with an IC50 of 0.21 nM[1].

[1]. Mehmet Kahraman, et al. Estrogen receptor modulator and uses thereof. WO2014205138A1.