N-Hydroxysulfosuccinimide (sulfo-NHS) is a modifying reagent that, in the presence of a cross-linking reagent like carbodiimide or EDAC, converts carboxyl groups to amine-reactive sulfo-NHS esters.
CAS：106627-54-7
分子式：C4H4NO6S.Na
分子量：217.1
纯度：98%
存储：Store at -20°C

Background:

N-Hydroxysulfosuccinimide (sulfo-NHS) is a modifying reagent that, in the presence of a cross-linking reagent like carbodiimide or EDAC, converts carboxyl groups to amine-reactive sulfo-NHS esters. The cross-linker converts the carboxylic acid to an unstable o-acylisourea intermediate, which then reacts with the primary amine of sulfo-NHS to produce the stable product.