OSMI-4是一种低纳摩尔的O-连接的N-乙酰半乳糖胺转移酶(OGT)的抑制剂，其在细胞中的EC50值为3μM。
CAS：2260791-14-6
分子式：C27H26ClN3O7S2
分子量：604.09
纯度：98%
存储：Store at -20°C

Background:

OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells.

OSMI-4 (4b) is the best OGT inhibitor reported to date, with a ～3 μM EC50 in cells, making it especially attractive for probing OGT’s complex biology[1].

[1]. Martin SES, et al. Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545.