Aspartyl-alanyl-diketopiperazine (DA-DKP) 是一种免疫调节分子，由人血白蛋白的 N 端裂解和环化产生，通过与 T 淋巴细胞无反应相关的分子途径调节炎症免疫反应。
CAS：110954-19-3
分子式：C7H10N2O4
分子量：186.17
纯度：98%
存储：Store at -20°C

Background:

Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy[1][2].

[1]. Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441(1):13-7. [2]. Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64(1):35-41.