Pinane thromboxane A2 (PTA2) is a stable analog of TXA2.
CAS：71111-01-8
分子式：C24H40O3
分子量：376.6
纯度：98%
存储：Store at -20°C

Background:

Pinane thromboxane A2 (PTA2) is a stable analog of TXA2. It is a TP receptor antagonist and an inhibitor of thromboxane synthase. PTA2 inhibits U-46619-induced cat coronary artery constriction (ID50 = 0.1 µM), U-46619-induced aggregation of human platelets (IC50 = 2 µM), and rabbit platelet thromboxane synthase (ID50 = 50 µM). PTA2 does not affect PGI synthase up to a concentration of 100 µM.