| CAS NO: | 163768-50-1 |
| 规格: | 98% |
| 分子量: | 745.99 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 50mg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
Background:
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
[1]. Temming K, et al. Improved efficacy of alphavbeta3-targeted albumin conjugates by conjugation of a novel auristatin derivative. Mol Pharm. 2007 Sep-Oct;4(5):686-94. [2]. Doronina SO, et al. Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity. Bioconjug Chem. 2006 Jan-Feb;17(1):114-24.
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