YKL-06-061 是有效的、选择性的盐诱导激酶 (SIK) 的二代抑制剂，其对SIK1/2/3 的IC50 值为6.56 nM/1.77 nM/20.5 nM。
CAS：2172617-15-9
分子式：C30H37N7O2
分子量：527.66
纯度：98%
存储：Store at -20°C

Background:

YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1]. IC50: 6.56 nM/1.77 nM/20.5 nM (SIK1/2/3)[1].

[1]. Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184.