8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis.
CAS：98462-03-4
分子式：C20H32O3
分子量：320.5
纯度：98%
存储：Store at -20°C

Background:

8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 µM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 µM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.