(R)-Gyramide A is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 μM.
CAS：1793050-70-0
分子式：C21H27FN2O3S.HCl
分子量：443
纯度：98%
存储：Store at -20°C

Background:

(R)-Gyramide A is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 µM. It does not affect the closely related enzyme topoisomerase IV. (R)-Gyramide A demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs range from 10-80 µM).