BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions.
CAS：2219331-30-1
分子式：C28H26FN5O
分子量：467.5
纯度：98%
存储：Store at -20°C

Background:

BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-F-Yne inhibits PAD1-4 with Kinact/KI values of 900, 1,200, 3,400, and 3,750 M-1min-1, respectively. It has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.