| CAS NO: | 18228-17-6 |
| 规格: | 98% |
| 分子量: | 377.72 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
Background:
KG-501 is a CREB inhibitor, with an IC50 of 6.89 μM.
KG-501, which directly targets the KIX domain of CBP, results in a disrupted CREB-CBP complex, inhibits CREB-target gene induction, and inhibits IL-1β-mediated angiogenic activity in NSCLC[1]. KG-501 disrupts phospho (Ser-133) CREB binding to KIX with a Ki of
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