Background:

Epipregnanolone is an endogenous neurosteroid that has anesthetic, hypnotic, and sedative properties.

[1]. Ayoola C, et al. Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone. Psychopharmacology (Berl). 2014 Sep;231(17):3503-3515.