Seclidemstat(SP-2577)是一种有效的LSD1抑制剂，平均IC50值为127nM。
CAS：1423715-37-0
分子式：C20H23ClN4O4S
分子量：450.94
纯度：98%
存储：Store at -20°C

Background:

Seclidemstat (SP-2577) is a potent LSD1 inhibitor, with a mean IC50 of 127 nM.

Seclidemstat (Compound 2577) reduces tumor volume at 40, 80 mg/kg by i.p. and also shows such effect at 80 mg/kg via p.o. dosing.

[1]. SUBSTITUTED BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIBITORS. WO/2017/004519 A1