Valilactone is an esterase inhibitor produced by a cultured strain of soil actinomycetes.
CAS：113276-96-3
分子式：C22H39NO5
分子量：397.6
纯度：98%
存储：Store at -20°C

Background:

Valilactone is an esterase inhibitor produced by a cultured strain of soil actinomycetes. It is reported to inhibit hog liver esterase and hog pancreas lipase with IC50 values of 29 and 0.14 ng/ml, respectively. Valilactone can also inhibit fatty acid synthase with an IC50 value of 0.30 µM and demonstrates selective toxicity towards MDA-MB-231 breast cancer cells with an IC50 value of 10.5 µM.