Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R.
CAS：37248-47-8
分子式：C20H35NO13
分子量：497.5
纯度：98%
存储：Store at -20°C

Background:

Validamycin A is an antifungal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R. solani, due to its ability to inhibit trehalase, a trehalose-hydrolizing enzyme (Ki = 1.9 nM; IC50 = 0.7 μM). It is also effective against the growth and sporulation of R. cerealis, F. culmorum, and other fungi. This compound has also been used to study trehalase activity and trehalose biosynthesis.