Apararenone(MT-3995)是新型非甾体类盐皮质激素受体(mineralocorticoidreceptor)拮抗剂，正在开发用于治疗糖尿病性肾病和非酒精性脂肪性肝炎。
CAS：945966-46-1
分子式：C17H17FN2O4S
分子量：364.39
纯度：98%
存储：Store at -20°C

Background:

Apararenone (MT-3995) is a novel non-steroidal mineralocorticoid receptor antagonists under development for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis.

Recently, a phase II clinical trial has been initiated among patients with non-alcoholic steatohepatitis (NASH) in Japan[1].

[1]. Kolkhof P, et al. 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor antagonists: 60 years of research and development. J Endocrinol. 2017 Jul;234(1):T125-T140.