ML-109是有效的、促甲状腺激素受体(TSHR)的全激动剂，其EC50值为40nM。
CAS：1186649-91-1
分子式：C31H29N3O5
分子量：523.58
纯度：98%
存储：Store at -20°C

Background:

ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM.

ML-109 (Compound 2) is a full agonist at TSHR with an EC50 of 40 nM and, like compound 1, it has no activity at FSHR or LHCGR. ML-109 contains an aminal, a functional group that is subject to hydrolysis and/or other degradation mechanisms. ML-109 is surprisingly stable at neutral and basic conditions (t1/2 of