| CAS NO: | 652968-37-1 |
| 包装: | 10mg |
| 规格: | 98% |
| 市场价: | 4694元 |
| 分子量: | 590.5 |
Background:
MitoPBN is a mitochondria-targeted antioxidant. It accumulates in the mitochondria following the generation of a mitochondrial membrane potential by succinate, an effect that is blocked by addition of the mitochondrial membrane potential uncoupler FCCP . MitoPBN inhibits superoxide activation of mitochondrial uncoupling protein 1 (UCP1), UCP2, and UCP3 when used at a concentration of 250 nM in vitro but does not react with superoxide. It traps hydroxyl (IC50 =
m.cnreagent.com