Nemorexant(ACT-541468)是一种orexin受体拮抗剂，详细信息请参考专利文献WO2015083094A1中的化合物example7。作用于Ox1和Ox2受体，IC50分别为2nM和3nM。
CAS：1505484-82-1
分子式：C23H23ClN6O2
分子量：450.92
纯度：98%
存储：Store at -20°C

Background:

Nemorexant (ACT-541468) is a potent orexin receptor antagonist extracted from patent WO2015083094A1, compound example 7, has IC50s of 2 nM and 3 nM for Ox1 receptor and Ox2 receptor, respectively.

Nemorexant (Compound example 7) is a orexin receptor antagonist with IC50s of 2 nM and 3 nM for Ox1 receptor and Ox2 receptor, respectively[1].

[1]. BOSS, Christoph, et al. USE OF BENZIMIDAZOLE-PROLINE DERIVATIVES. WO2015083094A1.