N-lysine methyltransferase SETD8 inhibitor
CAS：1620401-82-2
分子式：C23H35N5O2
分子量：413.56
纯度：98%
存储：Store at -20°C

Background:

UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC50 of 7.3 μM; selective over 15 other methyltransferases[1].

参考文献:
[1]. Ma A, et al. Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8. J Med Chem. 2014 Aug 14;57(15):6822-33.