L162389是一种有效的angiotensinAT1受体拮抗剂，Ki值为28nM。
CAS：169281-53-2
分子式：C31H38N4O4S
分子量：562.72
纯度：98%
存储：Store at -20°C

Background:

L162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.

L-162,389 stimulates phosphatidylinositol turnover, albeit only to a small percentage of the angiotensin response. L-162,389 acts as angiotensin antagonist with IC50 value of 105 nM[1].

[1]. Perlman S, et al. Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations. Mol Pharmacol. 1997 Feb;51(2):301-11.