Amrinone is an inhibitor of phosphodiesterase 3 (PDE3; IC50 = 19.5 μM).
CAS：60719-84-8
分子式：C10H9N3O
分子量：187.2
纯度：98%
存储：Store at -20°C

Background:

Amrinone is an inhibitor of phosphodiesterase 3 (PDE3; IC50 = 19.5 µM). It increases developed tension and contractile force in isolated cat papillary muscle. Amrinone (1-10 mg/kg) has positive inotropic effects, increasing the rate and force of heart contraction in anesthetized and unanesthetized dogs.