WYC-209是一种合成类视黄醇，能抑制恶性小鼠黑色素瘤肿瘤再生细胞(TRC)的增殖，IC50值为0.19μM。WYC-209主要细胞靶点是维甲酸受体(RARs)。
CAS：2131803-90-0
分子式：C20H20N2O3S
分子量：368.45
纯度：98%
存储：Store at -20°C

Background:

WYC-209 is a synthetic retinoid, which inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 of 0.19 μM. The primary cellular target of WYC-209 is retinoic acid receptors (RARs)[1]. Retinoic acid receptors[1]

[1]. Chen J, et al. Inhibition of cancer stem cell like cells by a synthetic retinoid. Nat Commun. 2018 Apr 11;9(1):1406.