Mutant IDH1 inhibitor 是一个有效的突变型 IDH1 R132H 的抑制剂，IC50 值小于 72 nM。
CAS：1429180-08-4
分子式：C25H34N6O3
分子量：466.58
纯度：98%
存储：Store at -20°C

Background:

Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of< 72 nM. IC50:< 72 nM (mutant IDH1 R132H)

Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer[1].

[1]. 3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404