5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE.
CAS：127708-42-3
分子式：C20H30O2
分子量：302.5
纯度：98%
存储：Store at -20°C

Background:

5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. The ability of (±)5-HETE lactone to inhibit rat basophilic leukemia cell 5-lipoxygenase (IC50 = 27 µM) may be entirely due to the 5(S) isomer, but the enantiomers have not been tested separately.