Background:

1-Methoxy PMS is stable electron-transport mediator between NAD(P)H and tetrazolium dyes.1-Methoxy PMS can induce active oxygen formation.

[1]. De Niz M et al. Tools for mass screening of G6PD deficiency: validation of the WST8/1-methoxy-PMS enzymatic assay in Uganda.Malar J. 2013 Jun 19;12:210. [2]. Arakawa H et al. Chemiluminescence assay for tetrahydrobiopterin based on the generation of hydrogen peroxide using isoluminol-microperoxidase in the presence of 1-methoxy PMS. Luminescence. 2007 May-Jun;22(3):245-50.