Gallopamil (Methoxyverapamil) 是一种维拉帕米的甲氧基衍生物 (methoxy derivative of verapamil)，也是一种苯基烷基胺钙 (phenylalkylamine calcium)拮抗剂。Gallopamil 可以作用于血管系统，心脏及其淋巴结构。Gallopamil 以浓度依赖性方式抑制酸分泌，IC50 为 10.9 μM.
CAS：16662-47-8
分子式：C28H40N2O5
分子量：484.63
纯度：98%
存储：Store at -20°C

Background:

Gallopamil (Methoxyverapamil), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist. Gallopamil acts on the vascular system and the heart and nodal structure[1]. Gallopamil inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM[2]. Ca2+

[1]. Brogden RN, et al. Gallopamil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in ischaemic heart disease. Drugs. 1994 Jan;47(1):93-115. [2]. Sewing KF, et al. Calcium channel antagonists verapamil and gallopamil are powerful inhibitors of acid secretion in isolated and enriched guinea pig parietal cells. Pharmacology. 1983;27(1):9-14.