TX1-85-1是一种Her3(ErbB3)抑制剂，IC50值为23nM。TX1-85-1可诱发Her3蛋白的部分降解并减弱Her3依赖性信号传导。
CAS：1603845-32-4
分子式：C32H36N8O3
分子量：580.68
纯度：98%
存储：Store at -20°C

Background:

TX1-85-1 is a Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling[1]. ErbB3|23 nM (IC50)

[1]. Xie T, et al. Pharmacological targeting of the pseudokinase Her3. Nat Chem Biol. 2014 Dec;10(12):1006-12.