(+)-JQ1 PA 是溴结构域和额外末端结构域 (BET) 抑制剂 JQ1 的衍生物，其 IC50 值为 10.4 nM。
CAS：2115701-93-2
分子式：C22H20ClN5OS
分子量：437.95
纯度：98%
存储：Store at -20°C

Background:

(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1, with an IC50 of 10.4 nM. 10.4 nM (BET)[1].

(+)-JQ1 PA is a derivative of JQ1, which is the inhibitor of BET. The IC50 of (+)-JQ1 PA for BET is 10.4 nM, and the IC50 of JQ1 is 14.3 nM in MV4;11 cells[1].

[1]. Tyler DS, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science. 2017 Jun 30;356(6345):1397-1401.