Seneciphylline is an alkaloid that has been found F.
CAS：480-81-9
分子式：C18H23NO5
分子量：333.4
纯度：98%
存储：Store at -20°C

Background:

Seneciphylline is an alkaloid that has been found F. japonicum and has diverse biological activites. It induces autophagy and decreases viability of Huh7.5 cells in a concentration-dependent manner. Seneciphylline is also cytotoxic to HepG2 cells (IC20 = 0.66 mM). Dietary administration of seneciphylline induces sex-linked recessive lethality in male Drosophila. Seneciphylline (80 mg/kg) increases the activity of epoxide hydrase and glutathione-S-transferase and decreases activity of cytochrome P450 and aminopyrine demethylase in rat liver.