| CAS NO: | 5874-97-5 |
| 规格: | 98% |
| 分子量: | 260.3 |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
Background:
Metaproterenol is a β2-adrenergic receptor (β2-AR) agonist with bronchodilator actions. It inhibits TGF-α-induced hepatocyte DNA synthesis and proliferation in vitro (IC50 = 15 nM), an effect that is reversed by the β2-AR antagonist butoxamine but not the β1-AR antagonist metoprolol . Metaproterenol dose-dependently relaxes lung strips and increases heart rate and inotropy of right atria and left atria, respectively, isolated from guinea pig (pD2s = 6.4, 7.08, and 6.61, respectively). Formulations containing metaproterenol were previously used as long-acting bronchodilators for the treatment of asthma.
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