Z-IETD-AFC is a fluorogenic substrate for caspase-8 and granzyme B.
CAS：219138-02-0
分子式：C37H42F3N5O13
分子量：821.8
纯度：98%
存储：Store at -20°C

Background:

Z-IETD-AFC is a fluorogenic substrate for caspase-8 and granzyme B. Upon enzymatic cleavage by caspase-8 or granzyme B, 7-amino-4-trifluoromethylcoumarin (AFC) is released and its fluorescence can be used to quantify caspase-8 or granzyme B activity. AFC displays excitation/emission maxima of 380/500 nm, respectively.