Background:

CDK-IN-2 is a potent and specific CDK9 inhibitor with IC50 of<8 nM, extracted from reference 1, example 4.IC50 Value:<8 nM [1]Target: CDK9In vitro:In vivo:

参考文献:
[1]. Keith B Pfister, et al. Heteroaryl compounds as kinase inhibitors. 2011, WO2011026917A1.