Armepavine 是一种来自 Nelumbo nucifera 的活性化合物，不仅对人外周血单核细胞具有抗炎作用，且对 T 淋巴细胞和狼疮肾炎小鼠也具有免疫抑制作用。Armepavine 抑制 TNF-α 诱导的 MAPK 和 NF-κB 信号级联反应。
CAS：524-20-9
分子式：C19H23NO3
分子量：313.39
纯度：98%
存储：Store at -20°C

Background:

Armepavine, an active compound from Nelumbo nucifera, exerts not only anti-inflammatory effects on human peripheral blood mononuclear cells, but also immunosuppressive effects on T lymphocytes and on lupus nephritic mice. Armepavine inhibits TNF-α-induced MAPK and NF-κB signaling cascades[1]. p65

[1]. Weng TC, et al. Inhibitory effects of armepavine against hepatic fibrosis in rats. J Biomed Sci. 2009 Sep 2;16:78.