Amauromine is a neutral antagonist of the cannabinoid (CB) receptor CB1 that is selective for CB1 (Ki = 178 nM; Kb = 66.6 nM) over CB2, with no activity at CB2 receptors at concentrations up to 10 μM.
CAS：88360-87-6
分子式：C32H36N4O2
分子量：508.7
纯度：98%
存储：Store at -20°C

Background:

Amauromine is a neutral antagonist of the cannabinoid (CB) receptor CB1 that is selective for CB1 (Ki = 178 nM; Kb = 66.6 nM) over CB2, with no activity at CB2 receptors at concentrations up to 10 µM. It is also an antagonist of GPR18 (IC50 = 3.74 µM). Amauromine has vasodilatory activity.