4-OctylItaconate是一种可透过细胞的Itaconate衍生物。Itaconate是一种抗炎代谢产物，通过KEAP1的烷基化而活化Nrf2。
CAS：3133-16-2
分子式：C13H22O4
分子量：242.31
纯度：98%
存储：Store at -20°C

Background:

4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

4-Octyl Itaconate (OI) is a cell-permeable itaconate derivative. 4-Octyl Itaconate is protective against lipopolysaccharide-induced lethality in vivo and decreases cytokine production[1].

[1]. Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.