MC-Val-Cit-PAB是可被组织蛋白酶切割的ADC连接桥，用于制备抗体-药物偶联物。 美国FDA批准的药物，如brentuximab vedotin使用了该连接桥。
CAS：159857-80-4
分子式：C28H40N6O7
分子量：572.65
纯度：98%
存储：Store at -20°C

Background:

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker. ADC linker[1]

[1]. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders